N-Desmethylapalutamide
CHEMICAL COMPOUND
N-desmethylapalutamide; Desmethylapalutamide; Desmethyl-apalutamide; N-Desmethyl-apalutamide; N-desmethyl-apalutamide; N-Desmethyl apalutamide; N-desmethyl apalutamide; Desmethyl apalutamide; Norapalutamide; Nor-apalutamide; C20H13F4N5O2S
N-Desmethylapalutamide is a nonsteroidal antiandrogen (NSAA) and the major active metabolite of apalutamide, an NSAA which is used as a hormonal antineoplastic agent in the treatment of metastatic prostate cancer. It has similar activity to that of apalutamide and, with apalutamide therapy, circulates at similar concentrations to those of apalutamide at steady state.